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Our Pipeline

Common Warts

VDMN:

Patient-Friendly, Injection-Free Approach for Common Warts

VDMN offers the potential to transform the standard of care for common warts (verruca vulgaris), a viral skin infection caused by human papillomavirus (HPV). Common warts affect approximately 19 million Americans and result in approximately 2.2 million visits with a healthcare provider annually in the U.S. alone. Common warts may persist for years without treatment. Currently, there are no FDA-approved prescription treatments for this condition.

 

VDMN is an investigational, proprietary, dissolvable microarray patch technology that administers immunotherapy within the superficial aspect of the skin. It is anticipated that this first-in-category technology will provide an “injection-free” immunotherapy treatment for common warts without creating the degree of pain, “needle-phobia,” and anxiety associated with traditional injections. VDMN has the potential to become a preferred treatment approach for children and young adults where aversion to painful procedures involving needles or freezing with liquid nitrogen and common wart prevalence are at their highest.
 

Injection-free Approach For Common Warts

VERRUCA VULGARIS

Common Warts

19M

Prevalence (U.S.)

2.2M

annual doctors' visits

2

Common Warts

NO FDA-APPROVED PRESCRIPTION TREATMENTS

OTC AND OFF-LABEL TREATMENTS
are either painful, scare children, or require burdensome daily applications for months

WARTVIRUS.png

INTRALESIONAL IMMUNOTHERAPY 

is FDA-approved and has been
used successfully off-label for treatment of warts for ~20 years

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BUT immunotherapy must be injected into the wart which is painful and requires in office administration

Source: 1. Kwong, P. Prevalence of Common Warts in the United States: Findings From General Population and Physician-Focused Surveys. Annual Fall Clinical Dermatology Conference. 2019, 2. Biotech Value Advisors (BVA) Syndicated Data, Based on Claims Data Analysis, 2021.

Core Microarray Technology

Product Drug

Adhesive

Backing

CORE MICROARRAY TECHNOLOGY

​

Core Microarray Technology Has Been Studied in 300+ Humans Including Infants Across 3 Clinical Trials


Tolerability of the Microarray and Efficacy of the Microarray as an Immune Stimulant are Confirmed by All Trials to Date

BIOLOGIC PRODUCT:

CANDIDA ANTIGEN EXTRACT

​

Candida Antigen's Safety Profile is Well-Characterized as it Has Been Administered to Hundreds of Thousands of People Globally

 

Primary AEs are Grade 1 Local Skin Reactions

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